The game may glitch in some live-with missions, where the objective NPC will become stuck behind a wall, and thus cannot be targeted. He may appear briefly, but you will not be able to maintain a lock on him. Walk towards the wall and enter the /kneel action to see through the wall. You can then click and target the NPC to complete your mission objective.
Save From Crashes
Save your character state frequently to protect from crashes. Simply open the skill menu and click "Accept." This will save your character's experience, and will allow you to load from this point in the event of a crash.
Save Screenshot
Press [F12] during gameplay to save a screenshot in the "/funcom/anarchy online/screenshots" folder.
Submit Bug Report
Press [Ctrl] + [Alt] + [Shift] + [F9] during gameplay.